gene 628 words KG: WRN
Contents

WRN — Werner Syndrome RecQ Like Helicase

🧬 Gene Info
Gene SymbolWRN
Full NameWerner Syndrome RecQ Like Helicase
AliasesPage for WRN Protein
Protein TypeEnzyme
FunctionWRN is a multifunctional DNA metabolic enzyme:
Molecular Weight164 kDa
Ensembl IDENSG00000113240
GeneCardsWRN
Human Protein AtlasWRN
Base excision repair (BER)Processing of oxidative DNA damage
DNA double-strand break repairHomologous recombination and NHEJ
Telomere maintenancePrevents telomere dysfunction
Replication fork restartResolves stalled replication forks
Associated DiseasesAging, Ms, Senescence
InteractionsCOMPLEMENT, CTC1, LMNA, MDM2, MRE11, MUTYH
KG Connections26 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

TREX1 interacts_with WRN
VCP interacts_with WRN
NEIL1 interacts_with WRN
POLD1 interacts_with WRN
POT1 interacts_with WRN
MRE11 interacts_with WRN
MUTYH interacts_with WRN
SAMHD1 interacts_with WRN
NBS1 interacts_with WRN
LMNA interacts_with WRN

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