gene 884 words KG: TLR2
Contents

TLR2 — Toll-Like Receptor 2

🧬 Gene Info
Gene SymbolTLR2
Full NameToll-Like Receptor 2
Chromosome4q31.3
Protein TypeReceptor
FunctionTLR2 is expressed in microglia, astrocytes, and neurons throughout the brain.
Primary Expressionmicroglia, astrocytes, and neurons throughout the brain
Amino Acids784 aa
Exons3
PathwaysNF-κB, PI3K
UniProt IDQ9Y257
NCBI Gene ID7103
Ensembl IDENSG00000137462
OMIM603028
GeneCardsTLR2
Human Protein AtlasTLR2
Associated DiseasesAls, Alzheimer, Brain Injury, Fibrosis, HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Known Drugs/CompoundsC29
InteractionsAKT, ALPHA-SYNUCLEIN, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND
KG Connections685 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

TLR2 Recognition of Gut-Derived Fungal and Bacterial D-Alany
Score: 0.55
Cross-Seeding: Gut Microbiome-Derived Bacterial Curli and Fu
Score: 0.54

Knowledge Graph (12 edges)

TLR2 regulates C3
LAMP2 therapeutic_target TLR2
TFRC therapeutic_target TLR2
PPP1CB therapeutic_target TLR2
TLR2 therapeutic_target MTOR
TLR2 therapeutic_target BID
TLR2 therapeutic_target BAD
CD47 associated_with TLR2
TLR2 associated_with CD36
TLR2 interacts_with CMKLR1

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