concept

SLC20A2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC20A2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

58Connections

0Hypotheses

0Analyses

39Outgoing

19Incoming

0Experiments

0Debates

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💡 Concept Info

Name	SLC20A2
Key Genes/Proteins	CMPK2, GENES, JAM2, JUN, MITOCHONDRIAL DYSFUNCTION
Related Diseases	Aging, Als, ALS, Basal Ganglia Calcifications, Fahr_disease
Related Pathways	Blood-Brain Barrier

Pathway Diagram

graph TD
    SLC20A2["SLC20A2"]
    SLC20A2 -->|"causes"| Basal_Ganglia_Calcifications["Basal Ganglia Calcifications"]
    SLC20A2 -->|"risk_factor_for"| Fahr_s_Disease["Fahr's Disease"]
    SLC20A2 -->|"regulates"| Ms["Ms"]
    SLC20A2 -->|"expressed in"| Als["Als"]
    SLC20A2 -->|"causes"| Fahr_disease["Fahr_disease"]
    SLC20A2 -->|"regulates"| XPR1["XPR1"]
    SLC20A2 -->|"regulates"| PDGFRB["PDGFRB"]
    GENES["GENES"] -->|"regulates"| SLC20A2
    PDGFRB -->|"regulates"| SLC20A2
    PDGFB["PDGFB"] -->|"regulates"| SLC20A2
    XPR1 -->|"regulates"| SLC20A2

Outgoing (39)

Target	Relation	Type	Str
Primary Familial Brain Calcification	associated_with	disease	0.95
Primary Familial Brain Calcification	causes	disease	0.95
Basal Ganglia Calcifications	causes	disease	0.93
Fahr's Disease	risk_factor_for	disease	0.90
phosphate homeostasis	regulates	process	0.85
Ms	associated_with	disease	0.65
Ms	expressed_in	disease	0.65
Aging	associated_with	disease	0.65
Parkinson	associated_with	disease	0.65
Ms	regulates	disease	0.65
Als	associated_with	disease	0.65
Als	expressed_in	disease	0.65
ALS	associated_with	disease	0.65
Fahr_disease	causes	disease	0.64
GENES	regulates	gene	0.60
Blood-Brain Barrier	associated_with	pathway	0.60
XPR1	associated_with	gene	0.60
XPR1	regulates	gene	0.60
GENES	associated_with	gene	0.60
JAM2	associated_with	gene	0.60
PDGFRB	regulates	gene	0.60
Pdgf	regulates	protein	0.60
Rb	regulates	protein	0.60
JUN	associated_with	gene	0.60
PDGFB	regulates	gene	0.60
PARKINSON	associated_with	gene	0.60
PDGFRB	associated_with	gene	0.60
PDGFB	associated_with	gene	0.60
PARKINSON'S DISEASE	associated_with	gene	0.60
Pdgf	associated_with	protein	0.60
Rb	associated_with	protein	0.60
XPR1	interacts_with	gene	0.60
MYORG	associated_with	gene	0.60
CMPK2	associated_with	gene	0.60
MITOCHONDRIAL DYSFUNCTION	associated_with	gene	0.60
Basal Ganglia	expressed_in	brain_region	0.55
Cerebellum	expressed_in	brain_region	0.55
White Matter	expressed_in	brain_region	0.55
Thalamus	expressed_in	brain_region	0.55

Incoming (19)

Source	Relation	Type	Str
JUN	associated_with	gene	0.60
JAM2	associated_with	gene	0.60
PDGFB	associated_with	gene	0.60
PDGFRB	associated_with	gene	0.60
GENES	associated_with	gene	0.60
XPR1	associated_with	gene	0.60
GENES	regulates	gene	0.60
PDGFRB	regulates	gene	0.60
PDGFB	regulates	gene	0.60
XPR1	regulates	gene	0.60
GENES	therapeutic_target	gene	0.60
MITOCHONDRIAL DYSFUNCTION	associated_with	gene	0.60
CMPK2	associated_with	gene	0.60
PARKINSON	associated_with	gene	0.60
CMPK2	interacts_with	gene	0.60
JAM2	interacts_with	gene	0.60
MYORG	interacts_with	gene	0.60
PDGFB	interacts_with	gene	0.60
PDGFRB	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SLC20A2 in their description or question text

No additional research found