Contents

TUBB3 Protein

🔬 Protein Info

Gene Symbol	TUBB3
Full Name	TUBB3 (βIII-Tubulin)
Chromosome	16q24.3
Protein Family	Tubulin family
Protein Type	Structural Protein
Target Class	Structural Protein
Function	TUBB3 performs essential neuronal functions:
Mechanism of Action	Small molecule stabilizers of microtubule structure or assembly
Druggability	Medium (0.49)
Clinical Stage	Approved
Molecular Weight	50 kDa
Amino Acids	450 aa
Pathways	Akt, Autophagy, Cell Cycle, Pi3K, Proteasome
UniProt ID	G3V3R4
Ensembl ID	ENSG00000198363
GeneCards	TUBB3
Human Protein Atlas	TUBB3
Associated Diseases	Alzheimer, Alzheimer's disease, Anoikis Resistance, Bone Metastasis, Huntington, Huntington's disease
Known Drugs/Compounds	rapamycin
Interactions	ACTB, Actin, ALZHEIMER, ALZHEIMER DISEASE, AND, APOPTOSIS
SciDEX Target	View Target Profile (8 clinical trials)
SciDEX Hypotheses	Quantum Coherence Disruption in Cellular Communica
KG Connections	424 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

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