protein 831 words KG: SYNJ1
Contents

SYNJ1 Protein

🔬 Protein Info
Gene SymbolSYNJ1
Chromosome21q22.11
Protein TypePhosphatase
FunctionSYNJ1 is crucial for synaptic vesicle cycling
Subcellular Localization</td><td>Presynaptic terminal, endocytic zone</td></tr>
Molecular Weight165 kDa
Amino Acids428 aa
Exons31
PathwaysEndosomal Sorting
UniProt IDSYNJ1
GeneCardsSYNJ1
Human Protein AtlasSYNJ1
Associated DiseasesAls, Cancer, Ms, Parkinson
InteractionsAD, ATP13A2, BIN1, DJ1, DNAJC6, FBXO7
KG Connections119 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (14)

Parkinson Basal Ganglia Circuit
circuit · KG edge: associated_with
NeuRon Therapeutics
company · KG edge: associated_with
Astrocytes
entity · KG edge: associated_with
Parkin (PARK2)
entity · KG edge: associated_with
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: associated_with

Knowledge Graph (12 edges)

PARKIN associated_with SYNJ1
LRRK2 associated_with SYNJ1
GAK associated_with SYNJ1
SYNJ1 associated_with DNAJC6
SYNJ1 associated_with PARK2
SYNJ1 associated_with VPS35
SYNJ1 associated_with PRKN
DNAJC6 associated_with SYNJ1
VPS35 associated_with SYNJ1
PRKN associated_with SYNJ1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)