| Gene Symbol | NURR1 |
| Full Name | Nuclear Receptor Related 1 (NURR1) |
| Protein Type | Protein |
| Target Class | Protein |
| Function | NURR1 is an orphan nuclear receptor with ligand-independent activity: |
| Mechanism of Action | Prioritized from 1 SciDEX hypotheses, including: Programmable Neuronal Circuit Repair via Epigenetic CRISPR |
| Druggability | Undruggable (0.23) |
| Amino Acids | 598 aa |
| Exons | 8 |
| Pathways | Alpha-Synuclein, Autophagy, Er Stress, Synaptic Plasticity |
| UniProt ID | Search UniProt |
| Ensembl ID | ENSG00000153234 |
| GeneCards | NURR1 |
| Human Protein Atlas | NURR1 |
| N-terminal AF-1 domain | Constitutive transcriptional activation |
| Associated Diseases | neurodegeneration, Parkinson, Parkinson's disease |
| Known Drugs/Compounds | levodopa |
| Interactions | AGING, ALPHA-SYNUCLEIN, AMPK, ascl1, ASCL1, AUTOPHAGY |
| SciDEX Target | View Target Profile |
| KG Connections | 204 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!