protein 697 words KG: CACNA1D
Contents

CACNA1D Protein

🔬 Protein Info
Gene SymbolCACNA1D
Chromosome3p21.1
Protein FamilyVoltage-gated calcium channel (Cav1) family
FunctionCACNA1D encodes the α1D subunit of voltage-dependent L-type calcium channels, also known as Cav1.3
Primary Expressionneurons, cardiac pacemaker cells, and endocrine cells
Subcellular LocalizationCell membrane, dendritic shafts, presynaptic terminals
Molecular Weight245 kDa
UniProt ID[Q01658](https://www.uniprot.org/uniprot/Q01658)
GeneCardsCACNA1D
Human Protein AtlasCACNA1D
Associated Diseasesneurodegeneration
InteractionsCACNA1A, CACNA1C, CACNA1E, cacna1f, CACNA1F, CACNA1G
KG Connections31 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (4)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (9)

CACNA1A — Calcium Channel Alpha-1A Subunit
gene · KG edge: associated_with
CACNA1C Gene
gene · KG edge: associated_with
CACNA1E Gene
gene · KG edge: interacts_with
CACNA1F — Calcium Voltage-Gated Channel Auxiliary Subun
gene · KG edge: interacts_with
CACNA1G Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

CACNA1A associated_with CACNA1D
CCS contributes_to CACNA1D
CACNA1C associated_with CACNA1D
CACNA2D2 associated_with CACNA1D
CACNA1F associated_with CACNA1D
CACNA1I associated_with CACNA1D
CACNA2D1 associated_with CACNA1D
CACNA1E associated_with CACNA1D
CACNA1H associated_with CACNA1D
CACNA1D associated_with CACNA1G

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