Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NINJ2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NINJ2 |
| Key Genes/Proteins | Akt, AKT, Cytokine, EGR1, Igf, IGF1 |
| Related Diseases | Fibrosis, Liver Fibrosis |
graph TD
NINJ2["NINJ2"]
NINJ2 -->|"interacts"| IGF1R["IGF1R"]
NINJ2 -->|"contributes to"| Liver_Fibrosis["Liver Fibrosis"]
NINJ2 -->|"activates"| Fibrosis["Fibrosis"]
NINJ2 -->|"activates"| EGR1["EGR1"]
NINJ2 -->|"activates"| AND["AND"]
NINJ2 -->|"activates"| PDGFRB["PDGFRB"]
NINJ2 -->|"activates"| PI3K["PI3K"]
NINJ2 -->|"activates"| IGF1["IGF1"]
AKT["AKT"] -->|"activates"| NINJ2
IGF1R -->|"activates"| NINJ2
PDGF["PDGF"] -->|"activates"| NINJ2
IGF1 -->|"activates"| NINJ2
PDGFRB -->|"activates"| NINJ2
PI3K -->|"activates"| NINJ2
EGR1 -->|"activates"| NINJ2| Target | Relation | Type | Str |
|---|---|---|---|
| Liver Fibrosis | contributes_to | disease | 0.95 |
| Fibrosis | activates | disease | 0.65 |
| EGR1 | activates | gene | 0.60 |
| PDGFRB | activates | gene | 0.60 |
| PI3K | activates | gene | 0.60 |
| IGF1 | activates | gene | 0.60 |
| Rb | activates | protein | 0.60 |
| Pdgf | activates | protein | 0.60 |
| Akt | activates | protein | 0.60 |
| Igf | activates | protein | 0.60 |
| IGF1R | activates | gene | 0.60 |
| T Cell | activates | cell_type | 0.60 |
| Hepatocyte | activates | cell_type | 0.60 |
| Insulin | activates | protein | 0.60 |
| Cytokine | activates | protein | 0.60 |
| T Cell | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NINJ2 in their description or question text
No additional research found