| Gene Symbol | MUL1 |
| Full Name | Mitochondrial E3 Ubiquitin Protein Ligase 1 |
| Chromosome | 1p36.22 |
| Protein Type | Ligase |
| Function | MUL1 encodes a mitochondrial outer membrane E3 ubiquitin protein ligase that plays crucial roles in mitochondrial dynamics, mitophagy, and apoptosis regulation. |
| Molecular Weight | 37 kDa |
| Pathways | Akt, Apoptosis, Mitochondrial Function, Mitophagy, Nf-Κb |
| UniProt ID | [Q9H3K2](https://www.uniprot.org/uniprot/Q9H3K2) |
| Ensembl ID | ENSG00000067082 |
| OMIM | 612148 |
| GeneCards | MUL1 |
| Human Protein Atlas | MUL1 |
| Mitophagy enhancers | Boosting MUL1 activity to improve mitochondrial quality control |
| Ubiquitin-proteasome modulators | Targeting MUL1-mediated degradation pathways |
| Mitochondrial protectants | Supporting mitochondrial function downstream of MUL1 |
| Associated Diseases | AD, ALI, Als, Alzheimer, Cancer |
| Interactions | ABCD3, ACETYL-COA, Actin, ADRB2, AKT, ALS |
| KG Connections | 588 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!