mechanism 2,523 words KG: AD
Contents

Microglial State Trajectory from Mobilization to Dysregulation in Alzheimer's Disease

Mechanism Info
NameAD
Key Genes/ProteinsA2M, AB, ABCA1, ABCB1, ABCD3, ABCG1
Related DiseasesAGE
Linked Hypotheses133 hypotheses

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Related Hypotheses (74)

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Ephrin-B2/EphB4 Axis Manipulation
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Heat Shock Protein 70 Disaggregase Amplification
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Sphingolipid Metabolism Reprogramming
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TREM2-Dependent Microglial Senescence Transition
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Netrin-1 Gradient Restoration
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Score: 0.58
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Score: 0.57
Glymphatic System-Enhanced Antibody Clearance Reversal
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Cryptic Exon Silencing Restoration
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Targeted Butyrate Supplementation for Microglial Phenotype M
Score: 0.80
← Prevpg 4/4

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Related Experiments (30)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
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clinical · proposed · Score: 0.40
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clinical · proposed · Score: 0.90
Brain Connectivity-Targeted tACS Trial in Early AD
clinical · proposed · Score: 0.51
Microglial TREM2 Agonist In Vivo Efficacy
validation · proposed · Score: 0.45

See Also (15)

ASL Perfusion Biomarkers for Alzheimer's Disease
biomarker · Pages share 18 hypotheses
Digital Biomarkers for Alzheimer's Disease
biomarker · Pages share 18 hypotheses
Dried Blood Spot Biomarker Test for Alzheimer's Disease
biomarker · Pages share 18 hypotheses
DTI Biomarkers for Alzheimer's Disease
biomarker · Pages share 18 hypotheses
EEG Biomarkers for Alzheimer's Disease
biomarker · Pages share 18 hypotheses

Knowledge Graph (12 edges)

GSS implicated_in AD
CYP2E1 implicated_in AD
IDH2 implicated_in AD
IDH1 implicated_in AD
VEGFA implicated_in AD
EEF1A1 implicated_in AD
APOB implicated_in AD
MET implicated_in AD
MCL1 implicated_in AD
SF3B1 implicated_in AD

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