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mechanism 1,717 words KG: Er Stress
Contents

ER Stress and Unfolded Protein Response in Progressive Supranuclear Palsy

⚙ Mechanism Info
NameEr Stress
Key Genes/ProteinsABCB1, Actin, ADSL, AGING, AIM2, AKT
Related DiseasesAging, Als, Alzheimer
Related PathwaysAkt

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Related Hypotheses (61)

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Score: 0.56Miro1-Mediated Mitochondrial Trafficking Enhancement Therapy
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Score: 0.54Lysosomal Membrane Repair Enhancement
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Score: 0.51
← Prevpg 3/4Next →

Related Analyses (30)

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neurodegeneration · archived

Related Experiments (23)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Metabolic Pathway-Targeted Therapy in ALS
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clinical · proposed · Score: 0.40

See Also (15)

Packard Center for ALS Research
institution · KG edge: mediatesABCA7 (Redirect)
redirect · KG edge: causesAKT1 Gene
gene · KG edge: therapeutic_targetAging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activatesAIM2 Inflammasome Modulation Therapy for Neurodegenerat
idea · KG edge: activates

Knowledge Graph (12 edges)

CERS2 associated_with Er Stress
HSPA1A activates Er Stress
ERK1 activates Er Stress
JUN regulates Er Stress
G3BP1 regulates Er Stress
VALOSIN regulates Er Stress
VCP regulates Er Stress
CXCL2 inhibits Er Stress
IL6 inhibits Er Stress
ATF4 activates Er Stress

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