gene 557 words KG: IDH1
Contents

IDH1 Gene - Isocitrate Dehydrogenase 1

🧬 Gene Info
Gene SymbolIDH1
Full NameIsocitrate Dehydrogenase 1 (NADP+)
AliasesPage for IDH1 Gene, Page for IDH1 Protein
Chromosome2q33.3
Protein TypeEnzyme
FunctionIDH1 is a NADP+-dependent enzyme localized primarily in the cytosol and peroxisomes.
Molecular Weight47 kDa
PathwaysEpigenetic
UniProt IDO75874
NCBI Gene ID3417
Ensembl IDENSG00000138449
GeneCardsIDH1
Human Protein AtlasIDH1
Associated DiseasesAD, ADH, Aging, ALI, Als, AMI
InteractionsADRA2A, ALDH1A2, AND, APOB, ASTROCYTE, CANCER
KG Connections372 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

IDH1 activates MTOR
IDH1 inhibits IDH2
IDH1 therapeutic_target VEGFA
IDH1 therapeutic_target MDM4
IDH1 therapeutic_target APOB
IDH1 therapeutic_target SF3B1
IDH1 therapeutic_target MET
IDH1 therapeutic_target SMARCA4
IDH1 therapeutic_target TERT
IDH1 therapeutic_target JUN

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