gene 1,662 words KG: HNF4A
Contents

HNF4A - Hepatocyte Nuclear Factor 4 Alpha

🧬 Gene Info
Gene SymbolHNF4A
Full NameHepatocyte Nuclear Factor 4 Alpha
Chromosome20q13.12
Protein TypeReceptor
Functionis a nuclear receptor transcription factor that plays essential roles in metabolic regulation, organ development, and cellular homeostasis.
Primary Expressionneurons across multiple regions
Amino Acids465 aa
Exons13
PathwaysAmyloid
UniProt ID[P41235](https://www.uniprot.org/uniprot/P41235)
Ensembl IDENSG00000101076
GeneCardsHNF4A
Human Protein AtlasHNF4A
Promoter P1Drives expression in liver, pancreas, and kidney
Promoter P2Active in brain, muscle, and other tissues
Associated DiseasesHepatitis
InteractionsAKT, AKT1, AND, AXIN1, CANCER, CCND1
KG Connections97 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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IL6 activates HNF4A
HNF4A activates IL6R
HNF4A regulates STAT3
ABCD3 regulates HNF4A
HNF4A expressed_in GAD2
HNF4A regulates USH1C
MYC associated_with HNF4A
AKT1 inhibits HNF4A
HNF4A inhibits AKT
YAP1 regulates HNF4A

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