gene 1,152 words KG: VIM
Contents

VIM Gene

🧬 Gene Info
Gene SymbolVIM
Full NameVimentin
Chromosome10p13
Functionencodes a type III intermediate filament protein that is one of the most widely expressed structural proteins in eukaryotic cells.
Molecular Weight57 kDa
Amino Acids466 aa
Exons9
PathwaysAutophagy, Immune Response, Mapk, Notch Signaling, Proteasome
Ensembl IDENSG00000026025
OMIM193060
GeneCardsVIM
Human Protein AtlasVIM
Associated DiseasesDiabetes, Inflammation, Parkinson, Parkinson's disease
Known Drugs/CompoundsColumbianadin, rapamycin
InteractionsACTB, AMPK, ANXA2, AQP4, AR, ASTROCYTES
KG Connections373 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (13)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Aquaporin-4 Polarization Rescue
Score: 0.73
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54

Related Analyses (6)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

See Also (15)

Apoptosis in Neurodegeneration
entity · KG edge: biomarker_for
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: biomarker_for
Astrocytes
entity · KG edge: activates
ACTB Gene
gene · KG edge: regulates
ANXA2 — Annexin A2
gene · KG edge: activates

Knowledge Graph (12 edges)

ACTB regulates VIM
CDC42 regulates VIM
CASP3 regulates VIM
SQSTM1 associated_with VIM
TUBB3 associated_with VIM
STK11 associated_with VIM
VIM regulates BECN1
VIM associated_with HDAC6
VIM regulates GAPDH
VIM associated_with MAP1LC3B

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