gene 957 words KG: ULK3
Contents

ULK3 Gene

🧬 Gene Info
Gene SymbolULK3
Full NameUnc-51 Like Kinase 3
Chromosome19q13.43
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious brain regions:
Molecular Weight102 kDa
Amino Acids300 aa
PathwaysAMPK, mTOR, mtor, PI3K
UniProt IDQ6ZNE5
NCBI Gene ID54586
Ensembl IDENSG00000140474
OMIM608866
GeneCardsULK3
Human Protein AtlasULK3
ULK1Primary autophagy initiator, phosphorylated by AMPK
Associated Diseasesneurodegeneration
InteractionsAND, BIN1
KG Connections18 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

APOE-Dependent Autophagy Restoration
Score: 0.88
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.82
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

NeuRon Therapeutics
company · KG edge: expressed_in
Neurodegeneration
disease · KG edge: implicated_in
Tumor Necrosis Factor (TNF)
entity · KG edge: therapeutic_target
AKT1 Gene
gene · KG edge: therapeutic_target
BIN1 — Bridging Integrator 1
gene · KG edge: activates

Knowledge Graph (12 edges)

TP53 therapeutic_target ULK3
SRC therapeutic_target ULK3
PI3K therapeutic_target ULK3
AKT therapeutic_target ULK3
AKT1 therapeutic_target ULK3
DRD4 expressed_in ULK3
ULK3 expressed_in DDIT3
BIN1 activates ULK3
IMMUNE INFILTRATION therapeutic_target ULK3
CANCER therapeutic_target ULK3

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