| Gene Symbol | TOLLIP |
| Full Name | Toll-Interacting Protein |
| Chromosome | 11p15.5 |
| Function | It binds and inhibits IL-1 receptor-associated kinase 1 (IRAK1), preventing its auto-phosphorylation and blocking downstream NF-kappaB and MAPK cascades. |
| Molecular Weight | 30 kDa |
| Amino Acids | 274 aa |
| Exons | 6 |
| Pathways | MAPK |
| UniProt ID | Q9H0E2 |
| NCBI Gene ID | 54472 |
| Ensembl ID | ENSG00000078902 |
| OMIM | 606277 |
| GeneCards | TOLLIP |
| Human Protein Atlas | TOLLIP |
| Associated Diseases | AD, ALI, Als, AMI, amyotrophic lateral sclerosis, degenerative disease |
| Interactions | ACTB, Actin, ALS, amyotrophic lateral sclerosis, AMYOTROPHIC LATERAL SCLEROSIS, AUTOPHAGY |
| KG Connections | 193 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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