gene 1,428 words KG: STAT5A
Contents

STAT5A Gene

🧬 Gene Info
Gene SymbolSTAT5A
Full NameSignal Transducer and Activator of Transcription 5A
Chromosome12q13
Functionis a member of the STAT (Signal Transducer and Activator of Transcription) family of transcription factors.
Primary Expressionneurons and glia, where it serves important functions: [@stat5a_neurons_2016]
Molecular Weight90 kDa
Amino Acids793 aa
Exons19
PathwaysJAK-STAT pathway
UniProt IDP42229
NCBI Gene ID6776
Ensembl IDENSG00000168661
OMIM601711
GeneCardsSTAT5A
Human Protein AtlasSTAT5A
Associated Diseasesneurodegeneration
InteractionsDLAT
KG Connections21 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.95
APOE-Dependent Autophagy Restoration
Score: 0.86
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Ocular Immune Privilege Extension
Score: 0.69
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66

Related Analyses (6)

Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (15)

JAK Inhibitors in Parkinson's Disease
company · KG edge: expressed_in
Neurodegeneration
disease · KG edge: implicated_in
Apoptosis in Neurodegeneration
entity · KG edge: expressed_in
STAT3 (Redirect)
redirect · KG edge: associated_with
Genes
index · KG edge: contributes_to

Knowledge Graph (12 edges)

DLAT activates STAT5A
JAK1 associated_with STAT5A
STAT6 associated_with STAT5A
JAK2 associated_with STAT5A
STAT2 associated_with STAT5A
STAT4 associated_with STAT5A
JAK3 associated_with STAT5A
STAT3 associated_with STAT5A
STAT1 associated_with STAT5A
JAK expressed_in STAT5A

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