gene 911 words KG: SOX11
Contents

SOX11 — SRY-Box Transcription Factor 11

🧬 Gene Info
Gene SymbolSOX11
Full NameSRY-Box Transcription Factor 11
Chromosome2p25.2
Protein TypeTranscription Factor
Functionis a member of the SOX (SRY-related HMG-box) family of transcription factors that play essential roles in neural development, neuronal differentiation, and cell fate specification.
Amino Acids497 aa
PathwaysEpigenetic
UniProt ID[P35746](https://www.uniprot.org/uniprot/P35746)
Ensembl IDENSG00000175087
GeneCardsSOX11
Human Protein AtlasSOX11
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsAND, CYCLIN D1, MYC
KG Connections16 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (10)

Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77
Epigenetic Memory Erasure via TET2 Activation
Score: 0.74
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.71
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
Quantum Coherence Disruption in Cellular Communication
Score: 0.63

Related Analyses (5)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (6)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
AAV Serotype Comparison for LRRK2 Knockdown in PD Gene Thera
validation · proposed · Score: 0.40
AAV-LRRK2 IND-Enabling Study Design
clinical · proposed · Score: 0.40
Epigenetic Dysregulation Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
Gene Therapy: AAV Serotype Comparison for LRRK2 Knockdown
validation · proposed · Score: 0.40

See Also (14)

Notch and Gamma-Secretase Modulators for Parkinson's Di
company · KG edge: therapeutic_target
Neurodegeneration
disease · KG edge: implicated_in
Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: activates
CD19 Gene
gene · KG edge: therapeutic_target
cdkn2a
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

CD19 therapeutic_target SOX11
TP53 therapeutic_target SOX11
SOX11 activates MYC
SOX11 therapeutic_target KMT2D
SOX11 therapeutic_target NSD2
SOX11 therapeutic_target NOTCH2
SOX11 therapeutic_target NFKBIE
SOX11 therapeutic_target CDKN2A
SOX11 therapeutic_target SMARCA4
SOX11 activates CYCLIN D1

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