gene 891 words KG: RAB3B
Contents

RAB3B Gene

🧬 Gene Info
Gene SymbolRAB3B
Chromosome1p31.1
FunctionThe RAB3B gene encodes a 219-amino acid protein that functions as a molecular switch in vesicle trafficking:
Primary Expressionneuronal and neuroendocrine cells, where they control synaptic vesicle dynamics essential for neurotransmission
Amino Acids219 aa
Ensembl IDENSG00000169258
GeneCardsRAB3B
Human Protein AtlasRAB3B
Associated DiseasesAls, Alzheimer, dementia, frontotemporal, neurodegeneration
InteractionsCALB2, CHRNA6, GFAP
KG Connections55 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Notch and Gamma-Secretase Modulators for Parkinson's Di
company · KG edge: contributes_to
FUS (Redirect)
redirect · KG edge: associated_with
GFAP (Redirect)
redirect · KG edge: inhibits
Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: inhibits
CALB2 Gene
gene · KG edge: inhibits

Knowledge Graph (12 edges)

RAB4B associated_with RAB3B
RAB27B associated_with RAB3B
RAB3C associated_with RAB3B
RAB5 associated_with RAB3B
RAB3B associated_with RAB5A
RAB3B associated_with RAB11B
RAB3B associated_with RAB10
RAB3B associated_with RAB3A
RAB3A associated_with RAB3B
RAB3B associated_with RAB3C

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