| Gene Symbol | RAB3A |
| Full Name | Ras-Related Protein Rab-3A |
| Function | is a synaptic vesicle-associated small GTPase that plays a central role in regulating neurotransmitter release[@raba2018][@rab2020]. |
| Subcellular Localization | </th><td>Synaptic Vesicles, Presynaptic Terminal</td></tr> |
| Molecular Weight | 25 kDa |
| Amino Acids | 35 aa |
| Pathways | Synaptic Vesicle Exocytosis |
| GeneCards | RAB3A |
| Human Protein Atlas | RAB3A |
| GTPase domain | Binds GTP/GDP and hydrolyzes to GDP |
| Switch I region | Conformationally changes between GTP/GDP states |
| Switch II region | Critical for effector interactions |
| Hypervariable C-terminal region | Geranylgeranylation for membrane anchoring |
| Polybasic region | Contributes to membrane association |
| C-terminal cysteine motif | CXXL for prenylation |
| Associated Diseases | Als |
| Interactions | AXON, GDI1, LRRK2, PARKINSON, PARKINSON'S DISEASE, RAB27B |
| KG Connections | 43 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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