gene 973 words KG: RAB10
Contents

rab10 Gene

🧬 Gene Info
Gene SymbolRAB10
Full NameRAB10, Member RAS Oncogene Family
Chromosome2
Protein FamilyRab GTPase family
FunctionRAB10 encodes a member of the Rab GTPase family involved in intracellular membrane trafficking
Subcellular LocalizationRAB10 localizes to:
Molecular Weight23 kDa
ExonsMultiple protein-coding exons spanning approximately 15 kb
PathwaysAutophagy, Mitophagy, autophagy pathway, mitophagy
UniProt IDQ9Y2P8
NCBI Gene ID10890
Ensembl IDENSG00000100705
GeneCardsRAB10
Human Protein AtlasRAB10
Location2p22.3
Associated DiseasesAls, Parkinson
InteractionsActin, AND, APOE, APOE3, ATP8B1, AUTOPHAGY
KG Connections115 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (8)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
Membrane Cholesterol Gradient Modulators
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Parkinson Basal Ganglia Circuit
circuit · KG edge: activates
Mitochondria
entity · KG edge: activates
Parkin (PARK2)
entity · KG edge: activates
PINK1 (PTEN-Induced Kinase 1)
entity · KG edge: associated_with
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates

Knowledge Graph (12 edges)

RAB4B associated_with RAB10
RAB27B associated_with RAB10
RAB3C associated_with RAB10
RAB5 associated_with RAB10
RAB3B associated_with RAB10
RAB5A associated_with RAB10
RAB11B associated_with RAB10
RAB10 associated_with RAB3A
RAB29 inhibits RAB10
LRRK2 inhibits RAB10

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