| Gene Symbol | PRNP |
| Full Name | Prion Protein |
| Chromosome | 20p13 |
| Function | is a gene located on chromosome 20p13 that encodes the major prion protein (PrP), a glycosylphosphatidylinositol (GPI)-anchored glycoprotein of 253 amino acids[@genetic2003]. |
| Primary Expression | Cerebral cortex, Cerebellum, Hippocampus, Thalamus, Basal ganglia, Brainstem |
| Amino Acids | 253 aa |
| Pathways | Amyloid |
| UniProt ID | P04156 |
| NCBI Gene ID | 5621 |
| Ensembl ID | ENSG00000171867 |
| OMIM | 176640 |
| GeneCards | PRNP |
| Human Protein Atlas | PRNP |
| Associated Diseases | Aging, Als, Alzheimer, Creutzfeldt-Jakob, frontotemporal dementia |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, APP, BACE1, BDNF, CTSB |
| KG Connections | 112 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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