entity 1,035 words KG: PRNP
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PRNP (Prion Protein Gene)

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Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Ocular Immune Privilege Extension
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
Microbiome-Derived Tryptophan Metabolite Neuroprotection
Score: 0.43

Related Analyses (9)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (2)

Pre-Symptomatic Detection and Intervention Timing in Genetic
validation · proposed · Score: 0.40
Prion Strain Diversity and Selective Vulnerability in CJD
clinical · proposed · Score: 0.40

See Also (12)

Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: regulates
BACE1 (Redirect)
redirect · KG edge: associated_with
IL6 (Redirect)
redirect · KG edge: associated_with
ACE Gene
gene · KG edge: associated_with
BDNF Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TAU activates PRNP
PRNP associated_with Creutzfeldt-Jakob
SORL1 associated_with PRNP
IL1A associated_with PRNP
IL10 associated_with PRNP
PLAU associated_with PRNP
BDNF associated_with PRNP
PSEN1 associated_with PRNP
MAPT associated_with PRNP
IL6 associated_with PRNP

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