Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about creutzfeldt-jakob: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
creutzfeldt_jakob["creutzfeldt-jakob"]
Prion["Prion"]
creutzfeldt_jakob -->|"associated with"| Prion
disease["disease"]
creutzfeldt_jakob -->|"associated with"| disease
NEURODEGENERATIVE_DISEASE["NEURODEGENERATIVE DISEASE"]
creutzfeldt_jakob -->|"associated with"| NEURODEGENERATIVE_DISEASE
style creutzfeldt_jakob fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7| Target | Relation | Type | Str |
|---|---|---|---|
| FERROPTOSIS | associated_with | pathway | 0.60 |
| PROGRESSIVE SUPRANUCLEAR PALSY | associated_with | disease | 0.60 |
| NEURON | causes | cell_type | 0.60 |
| PARKINSON'S DISEASE | co_discussed | disease | 0.60 |
| TAU | regulates | gene | 0.60 |
| DLB | co_discussed | gene | 0.60 |
| Apoptosis | biomarker_for | pathway | 0.55 |
| NEURODEGENERATIVE DISEASE | associated_with | concept | 0.50 |
| Prion | associated_with | protein | 0.50 |
| disease | associated_with | disease | 0.50 |
| MULTIPLE SCLEROSIS | co_discussed | disease | 0.45 |
| STING | co_discussed | gene | 0.40 |
| LEWY BODY DEMENTIA | co_discussed | disease | 0.40 |
| FTD | co_discussed | disease | 0.40 |
| FRONTOTEMPORAL DEMENTIA | co_discussed | disease | 0.40 |
| Source | Relation | Type | Str |
|---|---|---|---|
| AND | associated_with | gene | 0.65 |
| NEURODEGENERATIVE DISEASES | associated_with | gene | 0.65 |
| PROTEIN MISFOLDING | associated_with | gene | 0.65 |
| APOPTOSIS | biomarker_for | gene | 0.65 |
| PER | biomarker_for | gene | 0.65 |
| PRNP | associated_with | gene | 0.65 |
| AND | expressed_in | gene | 0.65 |
| CJD | co_discussed | gene | 0.60 |
| CJD | expresses | gene | 0.60 |
| CORTICOBASAL DEGENERATION | associated_with | disease | 0.60 |
| AD | regulates | gene | 0.60 |
| CJD | regulates | gene | 0.60 |
| ALZHEIMER'S DISEASE | co_discussed | disease | 0.60 |
| CJD | causes | gene | 0.60 |
| AD | associated_with | gene | 0.60 |
| ALZHEIMER'S DISEASE | associated_with | disease | 0.60 |
| AD | co_discussed | gene | 0.60 |
| CORTICOBASAL DEGENERATION | co_discussed | disease | 0.45 |
| AMYOTROPHIC LATERAL SCLEROSIS | co_discussed | disease | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning creutzfeldt-jakob in their description or question text
No additional research found