gene 2,808 words KG: PRKCD
Contents

PRKCD — Protein Kinase C Delta

🧬 Gene Info
Gene SymbolPRKCD
Full NameProtein Kinase C Delta
Chromosome1p36.11
Protein TypeSerine/Threonine Kinase
FunctionProtein kinase C delta (PKCδ) is a novel PKC isoform member of the protein kinase C family of serine/threonine kinases.
Primary Expressionneurons, astrocytes, microglia, and oligodendrocytes
Molecular Weight78 kDa
Amino Acids673 aa
PathwaysHifs
UniProt IDQ05639
NCBI Gene ID5580
Ensembl IDENSG00000163932
OMIM176977
GeneCardsPRKCD
Human Protein AtlasPRKCD
Associated DiseasesAls, Cancer, DNA fragmentation
InteractionsAkt, AUTOPHAGY, caspase-3, CBLN1, GLUD1, GRID1
KG Connections51 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (4)

APOE-Dependent Autophagy Restoration
Score: 0.85
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (5)

Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

See Also (15)

Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: inhibits
BECN1 Gene
gene · KG edge: expressed_in
BIRC5 (Survivin)
gene · KG edge: therapeutic_target
CBLN1 Gene
gene · KG edge: inhibits
CDKN1A — Cyclin-Dependent Kinase Inhibitor 1A
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

SQSTM1 inhibits PRKCD
MAP1LC3B inhibits PRKCD
GRID1 inhibits PRKCD
GLUD1 inhibits PRKCD
LAMP1 expressed_in PRKCD
PRKCD inhibits CBLN1
PRKCD expressed_in BECN1
PRKCD inhibits MAP1LC3B
PRKCD expressed_in LAMP1
PRKCD inhibits SQSTM1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)