gene 1,693 words KG: CDKN1B
Contents

CDKN1B — Cyclin-Dependent Kinase Inhibitor 1B

🧬 Gene Info
Gene SymbolCDKN1B
Full NameCyclin-Dependent Kinase Inhibitor 1B
Aliasesp27/Kip1
Protein TypeKinase
Functionis a member of the CIP/KIP family of cyclin-dependent kinase (CDK) inhibitors.
Amino Acids198 aa
Ensembl IDENSG00000100994
GeneCardsCDKN1B
Human Protein AtlasCDKN1B
Apoptosis regulationInteraction with ASK1 and modulation of JNK signaling
Associated DiseasesLupus
InteractionsAPP, BCL2L1, CD44, CTNNB1, CXCR4, HMGB1
KG Connections50 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
LRP1-Dependent Tau Uptake Disruption
Score: 0.60

Related Analyses (4)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: therapeutic_target
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
ATG16L2 Gene
gene · KG edge: associated_with
ATG5 — Autophagy Related 5
gene · KG edge: associated_with
ATG7 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

ATG16L2 associated_with CDKN1B
BECN1 associated_with CDKN1B
ATG5 associated_with CDKN1B
CDKN1B associated_with ATG7
CDKN1B associated_with RUBCN
CDKN1B associated_with CYBB
CDKN1B associated_with LRRK2
CDKN1B associated_with LC3
CDKN1B associated_with MAP1LC3B
CDKN1B associated_with DRAM1

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