gene 1,170 words KG: PRKCB
Contents

PRKCB — Protein Kinase C Beta

🧬 Gene Info
Gene SymbolPRKCB
Full NameProtein Kinase C Beta
Chromosome16p12.2
FunctionCell Proliferation and Differentiation: PKCβ signaling regulates cell cycle progression and phenotypic differentiation.
Subcellular Localizationpatterns. In the nervous system, PKCbeta plays critical roles in synaptic plasticity, learning and memory, neuronal surv
Amino Acids50 aa
UniProt ID[P05771](https://www.uniprot.org/uniprot/P05771)
Ensembl IDENSG00000166501
OMIM176970
GeneCardsPRKCB
Human Protein AtlasPRKCB
Associated DiseasesAls, Alzheimer, Cancer, Dementia, Ms, Tumor
InteractionsBST2, C3
KG Connections37 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

APOE-Dependent Autophagy Restoration
Score: 0.88
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (5)

Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

See Also (15)

Clusterin (ApoJ) - AD Biomarker
biomarker · KG edge: expressed_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: expressed_in
BECN1 Gene
gene · KG edge: expressed_in
BIN1 — Bridging Integrator 1
gene · KG edge: expressed_in
C3 — Complement Component 3
gene · KG edge: activates

Knowledge Graph (12 edges)

PRKCB activates C3
BIN1 expressed_in PRKCB
CDKN2A expressed_in PRKCB
PRKCB expressed_in CLU
PRKCB expressed_in BECN1
PRKCB expressed_in CLUSTERIN
PRKCB associated_with PIK3CG
MAPK3 therapeutic_target PRKCB
CDK6 therapeutic_target PRKCB
PRKCB therapeutic_target EGFR

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