gene 1,470 words KG: OPRM1
Contents

OPRM1 — Mu-Opioid Receptor

🧬 Gene Info
Gene SymbolOPRM1
Full NameMu-Opioid Receptor
Protein TypeProtein
Functionis a G protein-coupled receptor (GPCR) primarily known for its role in pain modulation, reward processing, and opioid drug responses[@minami1995].
Pathwaysautophagy pathway
UniProt IDSearch UniProt
GeneCardsOPRM1
Human Protein AtlasOPRM1
Associated DiseasesAddiction, Alzheimer, Alzheimer's disease, Anxiety, Dementia
InteractionsBDNF, DRD2, DRD4, GENES, OPRD1, PER
KG Connections102 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (11)

Noradrenergic-Tau Propagation Blockade
Score: 0.71
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.84
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (13)

ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: associated_with
ABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: associated_with
ADRA2A Gene
gene · KG edge: associated_with
ADRB2 Gene
gene · KG edge: associated_with
BCHE Gene - Butyrylcholinesterase
gene · KG edge: associated_with

Knowledge Graph (12 edges)

MAOB associated_with OPRM1
GABRA1 associated_with OPRM1
CHAT associated_with OPRM1
CYP2D6 associated_with OPRM1
APOE associated_with OPRM1
HMGCR associated_with OPRM1
OPRM1 associated_with SLC30A8
OPRM1 associated_with COMT
OPRM1 associated_with NBEA
OPRM1 associated_with HTR2C

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