gene 1,243 words KG: NBEA
Contents

NBEA — Neurobeachin

🧬 Gene Info
Gene SymbolNBEA
Full NameNeurobeachin
AliasesBCL8B
Chromosome13q13.1
Protein FamilyBEACH (Beige and Chediak-Higashi) family
FunctionScaffolding protein for protein kinase A, synaptic receptor trafficking
Primary ExpressionBrain (high), heart, lung, testis
Molecular Weight327.4 kDa
Amino Acids2946
Exons58 exons
PathwaysSynaptic plasticity, PKA signaling
UniProt IDQ8NFP9
NCBI Gene ID26045
Ensembl IDENSG00000172915
GeneCardsNBEA
Human Protein AtlasNBEA
Associated DiseasesAlzheimer, Alzheimer's disease, Anxiety, Dementia, Depression
InteractionsGENES, PER
KG Connections80 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (12)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Noradrenergic-Tau Propagation Blockade
Score: 0.71
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
APOE Isoform Conversion Therapy
Score: 0.72
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66

Related Analyses (2)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Genes
index · KG edge: associated_with
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: associated_with
ABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: associated_with
ADRA2A Gene
gene · KG edge: associated_with
ADRB2 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

MAOB associated_with NBEA
GABRA1 associated_with NBEA
CHAT associated_with NBEA
CYP2D6 associated_with NBEA
APOE associated_with NBEA
HMGCR associated_with NBEA
OPRM1 associated_with NBEA
SLC30A8 associated_with NBEA
COMT associated_with NBEA
NBEA associated_with HTR2C

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