gene 861 words KG: HTR2C
Contents

HTR2C Gene

🧬 Gene Info
Gene SymbolHTR2C
Full Name5-Hydroxytryptamine Receptor 2C
ChromosomeXq24
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe central nervous system
Molecular Weight70 kDa
PathwaysMAPK signaling
UniProt IDP28335
NCBI Gene ID3358
Ensembl IDENSG00000140048
OMIM312861
GeneCardsHTR2C
Human Protein AtlasHTR2C
Associated DiseasesAlzheimer, Alzheimer's disease, Anxiety, Autism, Bipolar
InteractionsCACNA1B, CACNA1H, DRD1, DRD2, GABRA1, GABRB2
KG Connections134 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (10)

Noradrenergic-Tau Propagation Blockade
Score: 0.71
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66

Related Analyses (5)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Bipolar Cells in Visual Processing
cell · KG edge: associated_with
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: associated_with
ABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: associated_with
ADRA2A Gene
gene · KG edge: associated_with
ADRB2 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

MAOB associated_with HTR2C
GABRA1 associated_with HTR2C
CHAT associated_with HTR2C
CYP2D6 associated_with HTR2C
APOE associated_with HTR2C
HMGCR associated_with HTR2C
OPRM1 associated_with HTR2C
SLC30A8 associated_with HTR2C
COMT associated_with HTR2C
NBEA associated_with HTR2C

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