| Gene Symbol | NURR1 |
| Full Name | Nuclear Receptor Related 1 |
| Protein Type | Protein |
| Target Class | Protein |
| Function | NURR1 is an orphan nuclear receptor with ligand-independent activity: |
| Mechanism of Action | Prioritized from 1 SciDEX hypotheses, including: Programmable Neuronal Circuit Repair via Epigenetic CRISPR |
| Druggability | Undruggable (0.23) |
| Amino Acids | 598 aa |
| Exons | 8 |
| Pathways | Alpha-Synuclein, Autophagy, Er Stress, Synaptic Plasticity |
| UniProt ID | Search UniProt |
| Ensembl ID | ENSG00000153234 |
| GeneCards | NURR1 |
| Human Protein Atlas | NURR1 |
| Associated Diseases | neurodegeneration, Parkinson, Parkinson's disease |
| Known Drugs/Compounds | levodopa |
| Interactions | AGING, ALPHA-SYNUCLEIN, AMPK, ascl1, ASCL1, AUTOPHAGY |
| SciDEX Target | View Target Profile |
| KG Connections | 204 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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