gene 1,604 words KG: NTN3
Contents

NTN3 Gene

🧬 Gene Info
Gene SymbolNTN3
Full NameNetrin 3
Chromosome16p13.3
Protein TypeReceptor
FunctionLike other netrins, NTN3 exerts its effects through binding to two main receptor families
Primary Expressionthe adult brain and may have roles in synaptic plasticity and repair
Molecular Weight71 kDa
Amino Acids641 aa
UniProt IDQ9Y2I2
NCBI Gene ID4904
Ensembl IDENSG00000118445
OMIM603389
GeneCardsNTN3
Human Protein AtlasNTN3
N-terminal domainContains laminin-like domains (VI and V) that mediate receptor binding
Associated DiseasesAD, ALI, Als, Alzheimer, Alzheimer's disease, disease
InteractionsAMYLOID, AND, DNA, NTN1, Proteins, PTN
KG Connections47 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Netrin-1 Gradient Restoration
Score: 0.59

Related Analyses (4)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (8)

Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: interacts_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: interacts_with
Complement System Dysregulation in Neurodegeneration -
gap · KG edge: expressed_in
JUN Gene
gene · KG edge: associated_with
NTN1 Gene - Netrin 1
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

TARDBP interacts_with NTN3
NTN1 interacts_with NTN3
SNRNP70 interacts_with NTN3
JUN expressed_in NTN3
JUN associated_with NTN3
NTN3 interacts_with SNRNP70
NTN3 interacts_with TARDBP
TAU interacts_with NTN3
NTN3 interacts_with TAU
NTN3 interacts_with NTN1

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