| Gene Symbol | NLRP6 |
| Full Name | NLR Family Pyrin Domain Containing 6 |
| Aliases | Page for NLRP6, Page for NLRP6 Protein, NACHT, LRR and PYD Domains-Containing Protein 6 |
| Protein Type | Receptor |
| Function | Mucus Secretion: NLRP6 regulates goblet cell mucus granule exocytosis and maintains the mucus barrier[@birchenough2016]. |
| Molecular Weight | 98 kDa |
| Amino Acids | 892 aa |
| Pathways | wnt |
| GeneCards | NLRP6 |
| Human Protein Atlas | NLRP6 |
| Inflammasome assembly | Forms inflammasome with ASC and caspase-1 |
| Cytokine production | Regulates IL-1β and IL-18 production |
| Gut homeostasis | Critical for intestinal epithelial cell function |
| [Autophagy](/entities/autophagy) | Regulates autophagic flux |
| Associated Diseases | Aging, ALS, Alzheimer, Autoimmune, Autoimmune Disease, Carcinoma |
| Interactions | AIM2, AKT, CANCER, CARD8, Caspase, Cytokine |
| KG Connections | 157 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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