gene 1,925 words KG: NLRP7
Contents

NLRP7 — NLR Family Pyrin Domain Containing 7

🧬 Gene Info
Gene SymbolNLRP7
Full NameNLR Family Pyrin Domain Containing 7
AliasesNOD27, CLR19.9
Chromosome19q13.42
Protein TypeReceptor
Functionis a member of the NOD-like receptor (NLR) family of proteins that plays complex roles in innate immunity, inflammation, and cellular homeostasis.
Amino Acids956 aa
Exons10
PathwaysInflammasome, Innate Immunity, pyroptosis
UniProt IDQ8WX94
NCBI Gene ID199713
Ensembl IDENSG00000124313
GeneCardsNLRP7
Human Protein AtlasNLRP7
Associated DiseasesAutoimmune
InteractionsAIM2, AND, CARD8, Caspase, Cytokine, CYTOKINES
KG Connections47 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (9)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.77
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62
LRP1-Dependent Tau Uptake Disruption
Score: 0.60

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (15)

Autoimmune Hypothesis in Alzheimer's Disease
hypothesis · KG edge: activates
NLRP2 — NLR Family Pyrin Domain Containing 2
gene · KG edge: activates
NLRP1 Gene
gene · KG edge: activates
NLRP6 - NLR Family Pyrin Domain Containing 6
gene · KG edge: activates
AIM2 Inflammasome Modulation Therapy for Neurodegenerat
idea · KG edge: interacts_with

Knowledge Graph (12 edges)

NLRP3 activates NLRP7
NLRP1 activates NLRP7
NLRP2 activates NLRP7
GAIN implicated_in NLRP7
NLRP6 activates NLRP7
NLRP7 activates NLRP12
NLRP7 activates CARD8
GAIN activates NLRP7
CARD8 activates NLRP7
NLRP7 activates NLRP1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.