| Gene Symbol | CARD8 |
| Full Name | Caspase Recruitment Domain Family Member 8 |
| Chromosome | 19q13.33. |
| Function | is a critical regulator of the innate immune inflammasome complex. |
| Primary Expression | neurons, astrocytes, and microglia, where it participates in n |
| Amino Acids | 541 aa |
| Pathways | Pyroptosis |
| UniProt ID | Q9Y2585 |
| NCBI Gene ID | 8912 |
| Ensembl ID | ENSG00000105464 |
| OMIM | 609508 |
| GeneCards | CARD8 |
| Human Protein Atlas | CARD8 |
| CARD Domain | Located at the N-terminus, this domain mediates protein-protein interactions with other CARD-containing proteins, particularly caspases |
| FIIND Domain | The function-to-find domain is required for the autoinflammatory processing of CARD8 |
| Associated Diseases | Als, Autoimmune, Cancer, Cardiovascular, Inflammation |
| Interactions | AIM2, AND, Caspase, Cytokine, CYTOKINES, GAIN |
| KG Connections | 87 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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