gene 585 words KG: NDUFS4
Contents

NDUFS4 Gene

🧬 Gene Info
Gene SymbolNDUFS4
FunctionThe NDUFS4 gene encodes NDUFS4 Protein, a protein involved in various cellular processes relevant to neuronal function and survival.
Primary Expressionvarious brain regions, with notable expression in: - Cerebral cortex - Hippocampus - Basal gang
PathwaysMicrorna
Ensembl IDENSG00000168907
GeneCardsNDUFS4
Human Protein AtlasNDUFS4
Associated DiseasesAlzheimer
InteractionsCOX15, COX4I1, COX7A1, COX8A, NDUFA12, NDUFA5
KG Connections19 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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Related Hypotheses (13)

CYP46A1 Overexpression Gene Therapy
Score: 0.98
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (6)

Neurodegeneration
disease · KG edge: implicated_in
Genes
index · KG edge: biomarker_for
HSP90AA1 Gene
gene · KG edge: biomarker_for
HSPE1 — Heat Shock Protein Family E Member 1
gene · KG edge: biomarker_for
OPTN — Optineurin
gene · KG edge: biomarker_for

Knowledge Graph (12 edges)

NDUFS4 biomarker_for HSPE1
NDUFS4 biomarker_for HSP90AA1
NDUFS4 biomarker_for OPTN
NDUFA5 co_expressed_with NDUFS4
NDUFS1 co_expressed_with NDUFS4
COX15 inhibits NDUFS4
COX4I1 inhibits NDUFS4
COX7A1 inhibits NDUFS4
COX8A inhibits NDUFS4
NDUFA12 inhibits NDUFS4

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