gene 1,616 words KG: IGF2BP2
Contents

IGF2BP2

🧬 Gene Info
Gene SymbolIGF2BP2
Full NameInsulin-like Growth Factor 2 mRNA-Binding Protein 2
AliasesGene profile: IGF2BP2
Chromosome9q33.3
Protein FamilyIMP/VICKZ RNA-binding protein family
Functionis an RNA-binding protein belonging to the IMP (IGF2BP/CRD-BP/VICKZ) family.
Primary Expressionembryonic development and cancer
Molecular Weight66 kDa
Amino Acids630 aa
Exons16
PathwaysAngiogenesis, Apoptosis, CRISPR-Cas, Epigenetic, Glycolysis
UniProt ID[Q9NZH8](https://www.uniprot.org/uniprot/Q9NZH8)
Ensembl IDENSG00000113721
GeneCardsIGF2BP2
Human Protein AtlasIGF2BP2
Associated DiseasesHead And Neck Squamous Cell Carcinoma, Poor Prognosis
InteractionsAND, APOPTOSIS, App, ATP, AUTOPHAGY, BRD4
KG Connections84 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (5)

Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
RNA Granule Nucleation Site Modulation
Score: 0.66

Related Analyses (3)

Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

ATP P2X3 Receptor Neurons
cell · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: inhibits
Genes
index · KG edge: activates
BRD4 (Bromodomain-Containing Protein 4)
gene · KG edge: encodes

Knowledge Graph (12 edges)

IGF2BP2 regulates LC3
IGF2BP2 activates PRKN
IGF2BP2 activates NOTCH1
IGF2BP2 interacts_with TRPM2
HNRNPU interacts_with IGF2BP2
MYC activates IGF2BP2
CSF1 activates IGF2BP2
CTCF activates IGF2BP2
EP300 interacts_with IGF2BP2
IGF2BP2 therapeutic_target CSF1R

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