gene 1,518 words KG: HNRNPU
Contents

HNRNPU Gene

🧬 Gene Info
Gene SymbolHNRNPU
AliasesHeterogeneous Nuclear Ribonucleoprotein U
Chromosome1q44.
Functionis a ubiquitously expressed nuclear matrix protein encoded by the HNRNPU gene located on chromosome 1q44.
Molecular Weight825 kDa
Amino Acids724 aa
Exons28
PathwaysEpigenetic, Nf-Κb
GeneCardsHNRNPU
Human Protein AtlasHNRNPU
Associated DiseasesAlzheimer's disease, Parkinson's disease, ALS
InteractionsCANCER, CCL2, CSF1, CSF1R, CTCF, EP300
KG Connections27 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

Axonal RNA Transport Reconstitution
Score: 0.70
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (8)

Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: activates
csf1
gene · KG edge: activates
CSF1R — Colony Stimulating Factor 1 Receptor
gene · KG edge: activates
CTCF Gene
gene · KG edge: interacts_with
EP300 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

HNRNPU activates MYC
HNRNPU activates CSF1
HNRNPU interacts_with CTCF
HNRNPU interacts_with EP300
HNRNPU interacts_with IGF2BP2
HNRNPU activates CSF1R
P38 activates HNRNPU
HNRNPU phosphorylates P38
HNRNPU activates P38
HNRNPU activates CANCER

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