gene 1,738 words KG: GRM5
Contents

GRM5 Gene - Metabotropic Glutamate Receptor 5

🧬 Gene Info
Gene SymbolGRM5
AliasesPage for GRM5 Gene
Protein TypeReceptor
FunctionmGluR5 mediates modulatory glutamate signaling
Subcellular LocalizationPlasma membrane, Dendritic spines
Molecular Weight132 kDa
Exons10
PathwaysMAPK
UniProt ID[P41594](https://www.uniprot.org/uniprot/P41594)
GeneCardsGRM5
Human Protein AtlasGRM5
Associated DiseasesAlzheimer, Autism, Bipolar, Cancer, Inflammation, Ms
InteractionsCACNA1B, CACNA1H, CDK5R2, DRD1, DRD2, FGF13
KG Connections117 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (6)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (10)

Cerebellum
brain · KG edge: expressed_in
Bipolar Cells in Visual Processing
cell · KG edge: associated_with
CACNA1B Gene
gene · KG edge: associated_with
CACNA1H Gene
gene · KG edge: associated_with
CDK5R2 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

GRM5 associated_with GABARAP
GRM5 associated_with GABRB1
SLC17A7 therapeutic_target GRM5
GRM5 therapeutic_target FGF13
GRM5 therapeutic_target CDK5R2
GABRB2 associated_with GRM5
SLC1A1 associated_with GRM5
SLC6A2 associated_with GRM5
GRIK4 associated_with GRM5
GRIA1 associated_with GRM5

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