gene 1,049 words KG: GNAQ
Contents

GNAQ Gene

🧬 Gene Info
Gene SymbolGNAQ
Full NameG Protein Subunit Alpha Q
Chromosome9q21.13
FunctionThe GNAQ protein is involved in transmitting signals from G protein-coupled receptors (GPCRs) on the cell surface to intracellular effector proteins.
Primary Expressionthe central nervous system and is particularly important for neuronal signaling, synaptic plasticity, and cellular responses to neurotransmitters and
PathwaysAkt, Pi3K
UniProt ID[P50148](https://www.uniprot.org/uniprot/P50148)
Ensembl IDENSG00000156052
GeneCardsGNAQ
Human Protein AtlasGNAQ
Calcium signalingModulation of neuronal excitability and synaptic transmission
PKC activationRegulation of ion channel function and gene expression
Cytoskeletal dynamicsControl of neuronal morphology and plasticity
Associated Diseasesneurodegeneration
InteractionsAKT, BRAF, ERK, ERK1, GENES, GNA11
KG Connections22 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Autophagosome Maturation Checkpoint Control
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Neurodegeneration
disease · KG edge: implicated_in
Genes
index · KG edge: activates
BRAF — B-Raf Proto-Oncogene, Serine/Threonine Kinase
gene · KG edge: activates
CDK2 Gene
gene · KG edge: associated_with
ERK1 (MAPK3) — Extracellular Signal-Regulated Kinase 1
gene · KG edge: activates

Knowledge Graph (12 edges)

BRAF activates GNAQ
PI3K activates GNAQ
ERK1 activates GNAQ
GNAQ activates STX17
GNAQ activates GNA11
GNAQ activates AKT
FYN associated_with GNAQ
MAPK3 associated_with GNAQ
PAK1 associated_with GNAQ
CDK2 associated_with GNAQ

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.