gene 861 words KG: FOXP2
Contents

FOXP2 Gene

🧬 Gene Info
Gene SymbolFOXP2
Full NameForkhead Box P2
Chromosome7q31.1
Protein TypeTranscription Factor
Functionencodes a transcription factor critically involved in neuronal development, synaptic plasticity, and speech/language acquisition.
Primary Expressionbasal ganglia, cortex, and cerebellum
Molecular Weight80 kDa
Amino Acids715 aa
Exons17
PathwaysMAPK
UniProt IDO15409
NCBI Gene ID2301
Ensembl IDENSG00000128573
OMIM605317
GeneCardsFOXP2
Human Protein AtlasFOXP2
Associated DiseasesAddiction, Als, Alzheimer, Autoimmune, Cancer, Carcinoma
InteractionsDISC1
KG Connections117 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (11)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
Transcriptional Autophagy-Lysosome Coupling
Score: 0.76
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
TREM2-mediated microglial tau clearance enhancement
Score: 0.62
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Bipolar Cells in Visual Processing
cell · KG edge: activates
blarcamesine-axon
clinical_trial · KG edge: regulates
ATF6 - Activating Transcription Factor 6
gene · KG edge: associated_with
BDNF Gene
gene · KG edge: associated_with
BMP7 Gene (Bone Morphogenetic Protein 7)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

DRD2 associated_with FOXP2
CHRNA5 associated_with FOXP2
FOXP2 associated_with DRD4
FOXP2 associated_with OPRM1
FOXP2 associated_with BDNF
FOXP2 associated_with SLC6A4
FOXP2 associated_with OVERVIEW
FOXP2 associated_with CHRNA5
FOXP2 associated_with DRD2
BDNF associated_with FOXP2

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