gene 725 words KG: FOXP1
Contents

FOXP1 Gene

🧬 Gene Info
Gene SymbolFOXP1
Chromosome3p13
Protein TypeTranscription Factor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionembryonic brain
Molecular Weight65 kDa
Amino Acids583 aa
Exons23
PathwaysCell Cycle, Complement, Oxidative Stress, Proteasome, Ubiquitin-Proteasome
GeneCardsFOXP1
Human Protein AtlasFOXP1
Associated DiseasesAls, Autism, Diabetes
Known Drugs/Compoundsquercetin
InteractionsActin, AURKA, Bdnf, BDNF, CDKN1A, C-FOS
KG Connections149 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (7)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Transcriptional Autophagy-Lysosome Coupling
Score: 0.76
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63

Related Analyses (4)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: activates
AURKA Gene
gene · KG edge: interacts_with
AVP Gene
gene · KG edge: biomarker_for
BDNF Gene
gene · KG edge: activates
BRCA2 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

AURKA regulates FOXP1
HSPA4 regulates FOXP1
FOXP1 regulates DNAJB1
CD38 therapeutic_target FOXP1
FOXP1 therapeutic_target TERT
FOXP1 therapeutic_target BRCA2
FOXP1 activates NLRP3
FOXA2 associated_with FOXP1
FOXO6 associated_with FOXP1
FOXO3 associated_with FOXP1

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