gene 3,323 words KG: FGF23
Contents

FGF23 — Fibroblast Growth Factor 23

🧬 Gene Info
Gene SymbolFGF23
Full NameFibroblast Growth Factor 23
Chromosome12p13
Functionencodes a hormone-like growth factor that belongs to the FGF19 subfamily of fibroblast growth factors.
Molecular Weight28.6 kDa
Amino Acids251 aa
UniProt IDQ9GZV9
NCBI Gene ID79581
Ensembl IDENSG00000166575
OMIM605380
GeneCardsFGF23
Human Protein AtlasFGF23
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsBDNF, CALRETICULIN, CX3CL1, CXCL10, Fgf, FGF21
KG Connections80 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (11)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam
Score: 0.79
Proteostasis Enhancement via APOE Chaperone Targeting
Score: 0.72
Glial Glycocalyx Remodeling Therapy
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48

Related Analyses (4)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (15)

CXCL10 - C-X-C Motif Chemokine Ligand 10
gene · KG edge: activates
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: biomarker_for
Complement System Dysregulation in Neurodegeneration -
gap · KG edge: biomarker_for
CX3CL1 — Fractalkine (C-X3-C Motif Chemokine Ligand 1)
gene · KG edge: activates
Packard Center for ALS Research
institution · KG edge: biomarker_for

Knowledge Graph (12 edges)

FGF21 activates FGF23
APP biomarker_for FGF23
FNDC5 activates FGF23
S100B biomarker_for FGF23
PLAU activates FGF23
CXCL10 activates FGF23
C1Q biomarker_for FGF23
CX3CL1 activates FGF23
VIM activates FGF23
BDNF activates FGF23

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