| Gene Symbol | FER |
| Full Name | FER Proto-Oncogene, Tyrosine Kinase |
| Chromosome | 5q31.2 |
| Protein Type | Receptor |
| Function | The FER gene encodes a non-receptor tyrosine kinase (Fer) that belongs to the FPS/FES family of tyrosine kinases. |
| Primary Expression | the brain and plays important roles in neuronal signaling, synaptic function, and cell adhesion[@fer2000] |
| Pathways | Ferroptosis, Oxidative Stress |
| UniProt ID | [P16591](https://www.uniprot.org/uniprot/P16591) |
| Ensembl ID | ENSG00000151422 |
| GeneCards | FER |
| Human Protein Atlas | FER |
| Postsynaptic density | Fer localizes to PSDs and phosphorylates PSD-95, affecting synaptic scaffolding |
| Receptor tyrosine kinases | Fer interacts with and regulates signaling from neurotrophin receptors |
| Synaptic plasticity | Fer activity modulates long-term potentiation (LTP) and long-term depression (LTD)[@yamada2019] |
| Associated Diseases | Stroke |
| Interactions | ACSL4, AKT, ALOX12, ALOX15, ALOX5, ALOXE3 |
| KG Connections | 209 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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