| Gene Symbol | FANCE |
| Chromosome | 6p21.31 |
| Protein Type | Adaptor Protein |
| Function | encodes an essential adaptor protein that plays a critical role in the Fanconi anemia (FA) DNA repair pathway. |
| Molecular Weight | 44 kDa |
| Amino Acids | 396 aa |
| Ensembl ID | ENSG00000112039 |
| GeneCards | FANCE |
| Human Protein Atlas | FANCE |
| Human-Mouse | 85% identical at the amino acid level |
| Human-Zebrafish | 72% identical |
| Drosophila | Partial ortholog with 45% identity |
| Yeast | No clear ortholog (FA pathway is metazoan-specific) |
| FANCD1 (BRCA2) | Required for homologous recombination |
| Associated Diseases | neurodegeneration |
| Interactions | ATM, ATR, DNA, FANCA, FANCC, FANCI |
| KG Connections | 24 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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