gene 3,327 words KG: FA2H
Contents

FA2H Gene

🧬 Gene Info
Gene SymbolFA2H
Chromosome16q23.1
FunctionFa2H Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Subcellular Localizationto the endoplasmic reticulum (ER) membrane in myelinating cells including oligod
Amino Acids383 aa
Exons13
PathwaysLipid Metabolism, Mitophagy, Autophagy
GeneCardsFA2H
Human Protein AtlasFA2H
Associated DiseasesALS, Dystonia, Ms, neurodegeneration, Parkinson
InteractionsATP13A2, CP, DCAF17, FTL, PANK2, PLA2G6
KG Connections24 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (12)

Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77
Epigenetic Memory Erasure via TET2 Activation
Score: 0.74
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.71
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
APOE-Dependent Autophagy Restoration
Score: 0.88
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Arginine Methylation Enhancement Therapy
Score: 0.65
Oligodendrocyte White Matter Vulnerability
Score: 0.65

Related Analyses (5)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
CRISPR Gene Correction Approaches for CBS/PSP
clinical · proposed · Score: 0.40
AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40
Peroxisomal Dysfunction Validation in Parkinson's Disease
validation · proposed · Score: 0.40

See Also (11)

Parkinson Basal Ganglia Circuit
circuit · KG edge: associated_with
Neurodegeneration
disease · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
C19orf12 Gene - Chromosome 19 Open Reading Frame 12
gene · KG edge: associated_with
COASY Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

FTL associated_with FA2H
WDR45 associated_with FA2H
COASY associated_with FA2H
DCAF17 associated_with FA2H
FA2H associated_with C19ORF12
FA2H associated_with PANK2
FA2H associated_with PLA2G6
FA2H associated_with neurodegeneration
FA2H interacts_with neurodegeneration
CP interacts_with FA2H

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