gene 562 words KG: CXCR3
Contents

CXCR3 Gene

🧬 Gene Info
Gene SymbolCXCR3
Full NameC-X-C Motif Chemokine Receptor 3
ChromosomeXq13.1
Protein TypeReceptor
FunctionCXCR3 is a chemokine receptor that plays critical roles in immune cell trafficking and signaling:
Molecular Weight40 kDa
Pathwayssignaling: ### Ligand Binding, PI3K, MAPK pathway
UniProt IDP49682
NCBI Gene ID2912
Ensembl IDENSG00000186810
OMIM300214
GeneCardsCXCR3
Human Protein AtlasCXCR3
Associated DiseasesAlzheimer's disease, Cancer, Carcinoma, disease, Inflammation
InteractionsAKT, AND, ASTROCYTES, AUTOPHAGY, BECN1, CANCER
KG Connections201 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (7)

Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.53
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.85
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73

Related Analyses (8)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

Astrocytes
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
BECN1 Gene
gene · KG edge: activates
CCL3 Gene
gene · KG edge: expressed_in
CCR1
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

CXCL10 interacts_with CXCR3
CXCR3 regulates TH1_RESPONSE
CXCL10 expressed_in CXCR3
CXCL10 activates CXCR3
LRP1 expressed_in CXCR3
CXCR3 expressed_in LRP1
CXCR3 interacts_with CD8
CXCR3 regulates LRP1
CXCR3 therapeutic_target MAP2
CXCR3 inhibits CXCL10

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)