gene 584 words KG: DRAM1
Contents

DRAM1 Gene

🧬 Gene Info
Gene SymbolDRAM1
Full NameDNA Damage Regulated Autophagy Modulator 1
Chromosome7q34
FunctionDRAM1 is a lysosomal membrane protein that acts as a key regulator of autophagy, a cellular process critical for clearing misfolded proteins and damaged organelles.
Molecular Weight37 kDa
PathwaysmTOR, mtor
UniProt IDDRAM1
NCBI Gene ID55332
Ensembl IDENSG00000138271
OMIM610686
GeneCardsDRAM1
Human Protein AtlasDRAM1
Associated DiseasesLupus
InteractionsAMPK, AUTOPHAGY, SNAP29, STIM1, STX17, ULK1
KG Connections39 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

APOE-Dependent Autophagy Restoration
Score: 0.88
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Autophagosome Maturation Checkpoint Control
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
mTOR Signaling Dysregulation in Progressive Supranuclea
event · KG edge: associated_with
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: regulates
ATG16L2 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

STX17 activates DRAM1
DRAM1 regulates STUB1
DRAM1 activates VAMP8
SNAP29 activates DRAM1
VAMP8 activates DRAM1
UBIQUITIN regulates DRAM1
DRAM1 activates SNAP29
ATG16L2 associated_with DRAM1
BECN1 associated_with DRAM1
ATG5 associated_with DRAM1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.