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index 475 words KG: GENES
Contents

Genes

🔬 Protein Info
Gene SymbolGENES
PathwaysAdaptive Immunity, Akt, Ampk Signaling, Amyloid, Angiogenesis
GeneCardsGENES
Human Protein AtlasGENES
Associated DiseasesAging, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Interactions6-OHDA, A2M, ABCA1, ABCA7, ABCB1, ABCG1
KG Connections7700 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

Wikipedia

Related Hypotheses (190)

Hypocretin-Neurogenesis Coupling Therapy
Score: 0.69Glycine-Rich Domain Competitive Inhibition
Score: 0.64Extracellular Vesicle Biogenesis Modulation
Score: 0.58Cryptic Exon Silencing Restoration
Score: 0.53ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.87Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79Competitive APOE4 Domain Stabilization Peptides
Score: 0.78Smartphone-Detected Motor Variability Correction
Score: 0.74Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72Noradrenergic-Tau Propagation Blockade
Score: 0.71Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65TREM2-mediated microglial tau clearance enhancement
Score: 0.62Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.90APOE-Dependent Autophagy Restoration
Score: 0.88Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
← Prevpg 2/10Next →

Related Analyses (27)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completedSEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · completedWhich cell types show the most significant expression change
neurodegeneration · completed

Related Experiments (28)

TREM2 Agonist Therapy for Parkinson's Disease — Experimental
validation · proposed · Score: 0.45TREM2 Function in Alzheimer's Disease — From Risk Variant to
validation · proposed · Score: 0.45Microglial TREM2 Agonist In Vivo Efficacy
validation · proposed · Score: 0.45Axonal Transport Dysfunction Validation in Parkinson's Disea
clinical · proposed · Score: 0.40s:** - Single-cell RNA-seq to measure editing efficiency acr
falsification · proposed · Score: 0.40

See Also (15)

OSK Reprogramming and Yamanaka Factors in Neurodegenera
mechanism · Pages share 6 hypothesesABCA2 Gene - ATP Binding Cassette Subfamily A Member 2
gene · KG edge: transportsABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: interacts_withABCG1 Gene
gene · KG edge: associated_withABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

FKBP4 associated_with GENES
MITOCHONDRIA biomarker_for GENES
HMGB1 biomarker_for GENES
GAIN interacts_with GENES
TGM2 biomarker_for GENES
VIMENTIN biomarker_for GENES
C1Q biomarker_for GENES
CX3CL1 biomarker_for GENES
PROGRANULIN biomarker_for GENES
APOPTOSIS biomarker_for GENES

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