gene 3,783 words KG: GBA
Contents

GBA Gene

🧬 Gene Info
Gene SymbolGBA
Functionis a critical gene in the intersection of lysosomal storage disorders and neurodegenerative diseases.
Molecular Weight60 kDa
Amino Acids536 aa
PathwaysAmyloid, Autophagy, Autophagy-Lysosomal Pathway, Chaperone, Epigenetic
Ensembl IDENSG00000177628
GeneCardsGBA
Human Protein AtlasGBA
Associated DiseasesAD, Aging, ALI, Als, Alzheimer
Known Drugs/CompoundsAAV.GMU01_SS3-GBA1, glucosylceramide, NCGC00188758
InteractionsABCD3, ACHE, Actin, AD, AGING, ALPHA-SYNUCLEIN
KG Connections1594 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Experiments (2)

Validate Mitochondria-Lysosome Contact Site Dysfunction in P
validation · proposed · Score: 0.40
LRRK2/GBA Mutation Carrier Resilience — Why Some Carriers Ne
validation · proposed · Score: 0.40

Knowledge Graph (12 edges)

CAT interacts_with GBA
OPTN interacts_with GBA
DNM1L interacts_with GBA
CANX interacts_with GBA
LGALS3 interacts_with GBA
CALCOCO2 interacts_with GBA
PEX3 interacts_with GBA
SQSTM1 interacts_with GBA
BCL2 interacts_with GBA
LMNA interacts_with GBA

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